2024 Phosphorylcholine phosphatase

Phosphorylcholine phosphatase

Author: prmy

August undefined, 2024

WebApr 27, 2012 · Pseudomonas Aeruginosa Phosphorylcholine Phosphatase. Monoclinic form PDB DOI: 10.2210/pdb4AS2/pdb Classification: HYDROLASE Organism (s): Pseudomonas aeruginosa Expression System: Escherichia coli BL21 Mutation (s): No Deposited: 2012-04-27 Released: 2012-08-22 Deposition Author (s): Infantes, L., Otero, L.H., Albert, A. … WebGene ID: 877730, updated on 12-Feb-2024. Summary Other designations. phosphorylcholine phosphatase. GeneRIFs: Gene References Into Functions. The structural comparison of PchP with other phosphatases of the haloacid dehalogenase family provides a three-dimensional picture of the conserved catalytic cycle and the structural basis for the …

The Structural Domains of Pseudomonas aeruginosa Phosphorylcholine …

WebJun 1, 2010 · Pseudomonas aeruginosa infections constitute a widespread health problem with high economical and social impact, and the phosphorylcholine phosphatase (PchP) of this bacterium is a potential target for antimicrobial treatment. However, drug design requires high-resolution structural information and detailed biophysical knowledge not … WebOther names in common use include phosphorylcholine transferase, CDP-choline pyrophosphorylase, CDP-choline synthetase, choline phosphate cytidylyltransferase, CTP-phosphocholine cytidylyltransferase, ... emoji chat apple

Masochistic enzymology: Dennis Vance

WebIn the presence of Mg(2+) or Zn(2+), PchP catalyzes the hydrolysis of p-nitrophenylphosphate (p-NPP) or phosphorylcholine (Pcho). The regulation of pchP gene … WebAug 21, 2012 · Phosphorylcholine phosphatases have been associated with the breakdown of the host cell membrane in bacteria [66] and therefore, their early expression suggests an important role in the switch to... Phosphorylcholine refers to the functional group derived from phosphocholine. Also not to be confused with phosphatidylcholine. Phosphorylcholine (abbreviated ChoP) is the hydrophilic polar head group of some phospholipids, which is composed of a negatively charged phosphate bonded to a small, positively charged choline group. Phosphorylcholine is part of the platelet-activating factor; the phospholipid phosph… teg blood lab

Phosphorylcholine phosphatase

WebPseudomonas aeruginosa synthesizes phosphorylcholine phosphatase (PchP) when grown on choline, betaine, dimethylglycine or carnitine. In the presence of Mg (2+) or Zn (2+), PchP catalyzes the... WebJun 7, 2024 · Studies support a colonization mechanism whereby P. aeruginosa can breakdown the host cell membrane phospholipids through the sequential action of two enzymes: (I) hemolytic phospholipase C acting upon phosphatidylcholine or …

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WebPcho is the product of the action of hemolytic phospholipase C (PlcH) on phosphatidylcholine or sphingomyelin and is hydrolyzed to choline and inorganic phosphate (Pi) by the action of PchP. Thus, both the PlcH and PchP enzymes are involved in the pathogenesis of P. aeruginosa [ 2 ]. WebDec 8, 2008 · Pseudomonas aeruginosa phosphorylcholine phosphatase (PChP), the product of the PA5292 gene, is synthesized when the bacteria are grown with choline, betaine, dimethylglycine, or carnitine.

WebThe substrate for PAP in the seminal plasma may be phosphorylcholine phosphate, which is rapidly hydrolyzed by the enzyme. However, the physiologic significance of the high levels … Webphosphorylcholine phosphatase. GeneRIFs: Gene References Into Functions. The structural comparison of PchP with other phosphatases of the haloacid dehalogenase family …

WebPhosphoethanolamine/phosphocholine phosphatase Chapter 678 Accesses Part of the Springer Handbook of Enzymes book series (HDBKENZYMES,volume S5) Keywords … WebThe phosphatidylcholine encountered in the host cell membranes allows the bacteria to obtain free choline by the coordinated action of PLC and Ac.Pase. Since the consequence of this action may be cell disruption, the increase of free carnitine in the natural environment of the bacteria is also possible.

WebJun 30, 2024 · Phosphocholine phosphatase-1 (PHOSPHO1) is a phosphocholine phosphatase that catalyzes the hydrolysis of phosphocholine (PC) to choline. Here we demonstrate that the PHOSPHO1 transcript is highly enriched in mature brown adipose tissue (BAT) and is further induced by cold and isoproterenol treatment …

WebThe increase of cholinesterase (ChE), acid phosphatase (Ac.Pase), and phospholipase C (PLC) activities byPseudomonas aeruginosa was associated with the choline consumption in growth media of varied composition (high or low Pi concentrations, presence or absence of ammonium ion, amino acids, polyamines, peptone, or tricarboxylic acid cycle … emoji centroWebPhosphoethanolamine/phosphocholine phosphatase Chapter 678 Accesses Part of the Springer Handbook of Enzymes book series (HDBKENZYMES,volume S5) Keywords Escherichia Coli Pseudomonas Aeruginosa Natural Substrate High Specific Activity Matrix Mineralization These keywords were added by machine and not by the authors. emoji ceske vlajkyWebApr 27, 2012 · 4AS2, 4AS3. PubMed Abstract: Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen. It colonizes different tissues by the utilization of diverse mechanisms. One of these may involve the breakdown of the host cell membrane through the sequential action of hemolytic phospholipase C and phosphorylcholine phosphatase … teg oltre limiteWebNov 2, 2012 · The action of hemolytic phospholipase C on phosphatidylcholine produces phosphorylcholine, which is hydrolyzed to choline (Cho) and inorganic phosphate by PchP. The available biochemical data on this enzyme demonstrate the involvement of two Cho-binding sites in the catalytic cycle and in enzyme regulation. emoji cgWebPhosphorylcholine. (Synonyms: Phosphocholine) Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal … teg kathuWebEffect of pH on Alkaline Phosphatase Activity of Human Intestinal Mucosa with Phenyl Phosphate ( ), Phosphorylethanolamine (•), Phosphorylcholine ( ) and Myo-inositol-2 … teg evaluationWebApr 27, 2012 · The action of hemolytic phospholipase C on phosphatidylcholine produces phosphorylcholine, which is hydrolyzed to choline (Cho) and inorganic phosphate by … teg live uk limited